Cornelia de Lange Syndrome Awareness Day serves as a dedicated occasion to bring attention to a relatively unfamiliar syndrome, often misdiagnosed as something else. Also known as CdLS, this genetic disorder is present at birth but is frequently diagnosed later in life. CdLS impacts both the intellectual and physical development of a child, potentially leading to significant developmental abnormalities.

Affecting an estimated 1 in 10,000 children, this awareness day takes place annually on the second Saturday in May. It encourages individuals to deepen their understanding of this disorder and contribute to organizations actively researching Cornelia de Lange Syndrome.